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Related Products

Monoclonal Antibodies To Coagulation Proteins
Polyclonal Antibodies to coagulation factors, antibody-peroxidase conjugates, etc.
Paired Antibodies for detection of individual coag factors

MONOCLONAL ANTIBODIES
TO COAGULATION PROTEINS

Anti-Human Factor V    Mab HFV

Binds human factor V in solid-phase ELISA.  Blots factor V and factor Va heavy chain.

Mab HFV Sample Certificate of Analysis


Anti-Human Factor VII  Mab HFVII

Binds human plasma and recombinant VII and VIIa in solid-phase ELISA.  Blots the light chain of non-reduced and reduced factor VIIa in immunoblot.  Specific for factor VII and does not cross-react with other vitamin k-dependent proteins.  Does not inhibit plasma factor VII clotting activity in Prothrombin Time assay. 

Mab HFVII Sample Certificate of Analysis


Anti-Human Factor VIII   Mab HFVIII

Binds human factor VIII in solid-phase ELISA.  Partial inhibition of APTT clotting assay.  Binds in presence of Ca2+ and EDTA.  Antibody if useful for depleting factor VIII from plasma.  Binds thrombin- and activated protein C-treated factor VIII.

Mab HFVIII Sample Certificate of Analysis


Anti-Human Factor IX   Mab HFIX

Binds human factor IX in solid-phase ELISA.  Blots human factor IX light chain.

Mab HFIX Sample Certificate of Analysis


Anti-Human Factor X  Mab HFX

Binds human factor X (HFX) in solid-phase ELISA and immunoblotting.

Mab HFX Sample Certificate of Analysis


Anti-Human Factor X Light Chain  Mab HFX-LC

Binds human factor X and Xa in solid-phase ELISA.  In immunoblotting, binds factor X light chain.  Bind 125I-labeled factor X.  Does not bind bovine factor X.  Binds factor X in presence of EDTA or CA2+.  Prolongs plasma prothrombin time (PT) and APTT.  Partially inhibits prothrombin activation in prothrombinase assay.

Mab HFX-LC Sample Certificate of Analysis


Anti-Human Factor X Heavy Chain  Mab HFX-HC

Binds human factor X and Xa in solid-phase ELISA.  In immunoblotting, binds factor X heavy chain.  Bind 125I-labeled factor X or bovine factor X.  Binds factor X in presence of EDTA or CA2+.  No effect on plasma prothrombin time (PT) and APTT.  Partially inhibits prothrombin activation in prothrombinase assay.

Mab HFX-HC Sample Certificate of Analysis


Anti-Human Factor XI  Mab HFXI

Binds human factor XI in solid-phase ELISA.

Mab HFXI Sample Certificate of Analysis


Anti-Human Factor XII  Mab HFXII

Binds human factor XII in solid-phase ELISA and immunoblotting techniques.

Mab HFXII Sample Certificate of Analysis


Anti-Human Factor XIII  Mab HFXIII

Binds human factor XIII in solid-phase ELISA and using immunoblotting techniques.

Mab HFXIII Sample Certificate of Analysis


Anti-Human Antithrombin  Mab HAT

Binds human antithrombin in solid-phase ELISA and immunoblotting techniques.

Mab HAT Sample Certificate of Analysis


Anti-Thrombin  Mab IIa

Binds human thrombin bound to polystyrene and in immunoblotting.  Antibody does  not bind prothrombin, prethrombin 1 or prethrombin 2, or bovine thrombin, bound to polystyrene.

Mab IIa Sample Certificate of Analysis


Anti-Human Prothrombin  Mab HFII

Binds human prothrombin, prethrombin 1 and fragment 2 (residues 156-271) in solid-phase ELISA.  Blots human prothrombin in Western blot.

Mab HFII Sample Certificate of Analysis


Anti-Human Protein C  Mab HPC

Binds human Protein C in solid-phase ELISA.  Blots non-reduced and heavy chain of reduced human Protein C.

Mab HPC Sample Certificate of Analysis


Anti-Human Tissue Factor  Mab TFE

Binds human tissue factor in solid-phase ELISA and immunoblotting techniques.  Binds human bladder carcinoma cells.

Mab TFE Sample Certificate of Analysis


Anti-Human vWF  Mab VWF

Binds human von Willebrand factor in solid-phase ELISA  and immunoblotting techniques.

Mab VWF Sample Certificate of Analysis


Anti-Human GPIIbIIIa  Mab GP2b3a

Binds glycoprotein IIb/IIIa complex from platelets  and megakaryocytes. Inhibits platelet aggregation and prolongs bleeding time. Binding requires calcium ion. Useful for immunofluorescence.

Mab GP2b3a Sample Certificate of Analysis


Anti-Plasminogen  Mab HPG

Binds Plasminogen immobilized onto plastic microtiter plates. Epitope is localized to "miniplasminogen" (residues 222-790).  Antibody blocks tPA, urokinase and streptokinase activation of Plasminogen.  No effect on plasmin chromogenic substrate activity.

Mab HPG Sample Certificate of Analysis


Anti-Vitronectin  Mab VN

Binds human vitronectin in solid-phase ELISA and immunoblotting techniques.

Mab VN Sample Certificate of Analysis


Anti-C4 Binding Protein  Mab C4BP

Binds human C4b binding protein in solid-phase ELISA.  Antibody coupled to sepharose can be used to purify C4bp from plasma.

Mab C4BP Sample Certificate of Analysis


Anti-PA Kringle 4  Mab PA K4

Binds human plasminogen, recombinant human angiostatin and isolated plasminogen kringle 4 in solid-phase and solution-phase ELISA, antibody binds only slightly to isolated plasminogen kringle 1-4 and does not bind plasminogen kringle fragment 1-3.  Antibody binds human plasminogen and recombinant angiostatin in immunoblotting procedures.

Mab PA K4 Sample Certificate of Analysis


Anti-PA Kringle 1-4  Mab PA K1-4

Binds recombinant human angiostatin and human plasminogen, specifically kringles 1-4, in solid-phase and solution-phase ELISA.  This antibody binds only slightly to isolated plasminogen kringle fragment 1-3 and the isolated plasminogen kringle fragment 4.  Antibody binds human plasminogen and recombinant angiostatin in immunoblotting procedures. 

Mab PA K1-4 Sample Certificate of Analysis


Anti-PA Kringle 1-3  Mab PA K1-3

Binds recombinant human angiostatin and human plasminogen, specifically kringles 1-3 and kringles 1-4, in solid-phase and solution-phase ELISA.  This antibody does not bind isolated plasminogen kringle fragment 4 or isolated plasminogen kringle fragment 5.  Antibody binds human plasminogen and recombinant angiostatin in immunoblotting procedures. 

Mab PA K1-3 Sample Certificate of Analysis


Anti-Human Fibrinogen  Mab FIB

 Binds human fibrinogen in solid-phase ELISA and immunoblotting procedures.

Mab FIB Sample Certificate of Analysis


Anti-Tissue Plasminogen Activator  Mab TPA

Binds human tissue plasminogen activator in a solid-phase ELISA. Antibody binds human tissue plasminogen activator in immunoblotting procedures.

Mab TPA Sample Certificate of Analysis


Anti-Human Thrombin Receptor B  Mab IIaB

Binds thrombin receptor peptide, SFLLRNPNDKYEPF in a solid-phase ELISA.  Does not inhibit platelet activation by thrombin.

Mab IIaB Sample Certificate of Analysis



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