BP 1004 Bovine
Prothrombin (Factor II)
Prepared from
freshly collected bovine plasma, bovine Prothrombin is a glycoprotein
of molecular weight 70,000 and consists of a single polypeptide chain.
Activation of Prothrombin by the prothrombinase complex (FXa, FVa, PL
and Ca++) yields the serine protease Thrombin. Prothrombin purity is
determined by SDS-PAGE and shows no reduction upon incubation with
2-mercaptoethanol.
Buffer composition = 20
mM Tris-HCl/0.1 M NaCl/pH 7.4
*Extinction Coefficient (1%) =14.4
One unit = 100 µg
Molecular Weight =70,000 daltons
Also available: des-Gla-Bovine Prothrombin
Bovine Prothrombin Sample Certificate of Analysis