BFIXa 1070
Bovine Factor IXaα
Prepared from Bovine Factor IX by activation with Russell's Viper Venom. This RVV-X
is removed after activation. The RVV-X is responsible for converting
Factor IX to an enzyme by cleavage of an internal Arg-Val peptide
bond. The Factor IXa produced by RVV-X cleavage possesses a molecular
weight identical to that of Factor IX but shows reduction upon incubation
with 2-mercaptoethanol. This form of Factor IXa has about 50% of the
coagulant activity of Factor IXaß.
Buffer composition = 20
mM Tris-HCl/0.1 M NaCl/pH 7.4
*Extinction Coefficient (1%) = 14.9
One unit = 5 µg
Molecular Weight = 55,400 daltons
Bovine Factor IXa Alpha Sample Certificate of Analysis