HFVII 1007 Human
Factor VII (Proconvertin)
Prepared from fresh frozen
human plasma. Human Factor VII is a single-chain vitamin K dependent
glycoprotein found in trace quantities in plasma (0.5 mg/Liter). In the Tissue Factor Pathway of coagulation, Human
Factor Vlla, in the presence of calcium ions and tissue factor, activates
Factors IX and X to their enzymatically active forms, Factor IXa and
Xa.
Buffer composition =20
mM Tris-HCl/0.1 M NaCl/1 mM Benzamidine/pH 7.4
*Extinction Coefficient (1%) = 13.9
Molecular Weight = 50,000 daltons
Human Factor VII Sample Certificate of Analysis