HP 1002
Human Prothrombin (Factor II)
Prepared from
fresh frozen human plasma. Human Prothrombin is a glycoprotein of
molecular weight 72,000, and consists of a single polypeptide chain.
Activation of Prothrombin by Factor Va, Xa and phospholipids yields the
serine protease Thrombin. Prothrombin purity is determined by SDS-PAGE
and shows no reduction upon incubation with 2-mercaptoethanol.
Buffer composition = 20
mM Tris-HCl/0.1 M NaCl/pH 7.4
*Extinction Coefficient (1%) = 13.6
One unit = 90 µg
Molecular Weight =72,000 daltons
Also available: des-Gla-Human Prothrombin and Prothrombin Fragment
1 and 2
Human Prothrombin Sample Certificate of Analysis