HFIXa 1080 Human
Factor IXa β
Prepared
from Human Factor IX by activation with Bovine Factor XIa. This
Bovine Factor XIa is removed after activation. Complete activation is
observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step
reaction. In the first step, an internal Arg-Ala bond is cleaved, and
in the second step, an Arg-Val bond is cleaved. The second cleavage
leads to the liberation of an activation peptide from the NH2-terminal
portion of the heavy chain to produce Factor IXaβ.
Buffer composition = 20 mM Tris-HCl/0.1 M NaCl /pH
7.4
*Extinction Coefficient (1%) = 14.3
One unit =5 µg
Molecular Weight = 45,000 daltons
Human Factor IXa Beta Sample Certificate of Analysis