α2AP
α2-Antiplasmin
α2-Antiplasmin
(α2AP), also known as α2Plasmin Inhibitor, is a plasma glycoprotein
that is a member of the SERPIN family of proteinase inhibitors.
α2AP is the primary fast-acting inhibitor of plasmin in vivo, but
has also been reported to inhibit other enzymes such as trypsin,
elastase, and Activated Protein C. α2AP is purified from normal human
plasma using immunoaffinity and ion-exchange chromatography. Purified α2AP activity
is determined by titration with purified plasmin.
Buffer Composition = 20 mM Tris-HCl/0.15 M NaCl/pH 7.3
Extinction Coefficient (1%) = 7.0
Molecular Weight = 70,000 daltons
a2 Antiplasmin Sample Certificate of Analysis