Human Activated Protein C

Human Activated Protein C

Catalog Number:
APC
Size:
0.1 mg, 1.0 mg

Activated Protein C (APC) is a serine protease derived from the two chain vitamin K dependent zymogen, Protein C. APC inhibits blood coagulation through the selective inactivation of the cofactors Va and VIIIa. APC is prepared from protein C by activation with purified thrombin. This thrombin is removed after activation by ion exchange chromatography. Activated Protein C purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.

Buffer composition = 20 mM Tris-HCl/0.1 M NaCl/ pH 7.4
Extinction Coefficient (1%) = 14.5
Molecular Weight = 56,000 daltons

Also available: des-Gla-Human Activated Protein C and Activated Protein C Inactivated

Human Activated Protein C Sample Certificate of Analysis