Human Protein C

Human Protein C

Catalog Number:
HPC 1001
0.1 mg, 1.0 mg

Purified from fresh frozen human plasma using a combination of salt precipitations and column chromatography. The protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Protein C is activated to the serine protease, Activated Protein C (APC), by a-thrombin or the complex of a-thrombin/thrombomodulin and is a potent anticoagulant through the selective inactivation of Factors Va and VIIIa.

Buffer composition = 20 mM Tris-HCl/0.1 M NaCl/1 mM Benzamidine/pH 7.4
Extinction Coefficient (1%) = 14.5
Molecular Weight = 62,000 daltons

Also available: des-Gla-Human Protein C

Human Protein C Sample Certificate of Analysis